Coronavirus is "running riot" across all age groups, Professor Calum Semple, a member of the Scientific Advisory Group for Emergencies (Sage), has warned.
Speaking in a personal capacity, he told BBC Radio 4's Today programme: "For the naysayers that don't believe in a second wave, there is a second wave.
"And unlike the first wave, where we had a national lockdown which protected huge swathes of society, this outbreak is now running riot across all age groups."
He added that there are "many more cases particularly in younger females between the ages of 20 and 40".
Professor Semple explained that there were three to four times as many women in the age group coming into hospital as men because they are exposed in hospitality, retail and some educational settings.
This information comes after the UK prepares for a second nationwide lockdown announcement from Prime Minister Boris Johnson later this afternoon.
Fears have arisen among the government that the predictions and modelling outstrip that of earlier this year when the first wave was at its peak.
It has become a concern for Boris Johnson that the majority of the country could enter tier 3 restrictions.
Halloween revellers enjoy one last night out on the town ahead of horror new lockdown
So a meeting with Health Secretary Matt Hancock, Chancellor Rishi Sunak and Michael Gove on Friday has led to the report that a nationwide lockdown could be announced as early as Monday.
Other options are on the table, however, including tier 4 restrictions.
New data published on Friday suggested around 570,000 people per week are becoming infected with Covid-19 across England, prompting fresh calls from scientists for tougher restrictions.
Boris Johnson addressing nation today as fears grow of second national lockdown
The Office for National Statistics (ONS) infection survey found cases "continued to rise steeply" in the week ending October 23, with an estimated 568,100 people in households becoming infected.
Shadow health secretary Jonathan Ashworth shared the Times newspaper front page, bearing the headline "national lockdown looms", as he said on Twitter: "The virus is now spreading with ferocity.
"Boris Johnson needs to show some actual leadership and get a grip of this crisis.
"He should have followed the advice of scientists and used the school half term for a time-limited circuit break to push infections down and save lives."
The prime minister will hold a news conference at the later time of 5pm today as an England-wide lockdown is considered.
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